Feldman Lab in the department of Pediatrics

Selected Publications

Tumor Autonomous Effects of Vitamin D Deficiency Promote Breast Cancer Metastasis.

Jasmaine D. Williams*, Abhishek Aggarwal*, Srilatha Swami, Aruna V. Krishnan, Lijuan Ji, Megan A. Albertelli and Brian J. Feldman. Endocrinology. In Press. *Shared first authors

Vitamin D Mitigates the Adverse Effects of Obesity on Breast Cancer in Mice

Swami SR, Krishnan AV, Williams J, Aggarwal A, Albetelli MA, Horst RL, Feldman BJ*, Feldman D* Endocr Relat Cancer. 2016 Jan 27. pii: ERC-15-0557. *Co-Senior and corresponding authors

Vitamin D Regulates Fatty Acid Composition in Subcutaneous Adipose Tissue Through Elovl3.

Ji L, Gupta M, Feldman BJ. Endocrinology. 2016 Jan;157(1):91-7

Mifepristone Treatment of Cushing's Syndrome in a Pediatric Patient.

Banerjee RR, Marina N, Katznelson L, Feldman BJ. Pediatrics. 2015 Oct 12. pii: peds.2015-0684. [Epub ahead of print] PMID: 26459648

Inhibition of Mouse Breast Tumor Initiating Cells by Calcitriol and Dietary Vitamin D.
Jeong Y, Swami S, Krishnan AV, Williams JD, Martin S, Horst RL, Albertelli MA, Feldman BJ, Feldman D, and M Diehn. Mol Cancer Ther. 2015 Aug;14(8):1951-61. doi: 10.1158/1535-7163.MCT-15-0066. Epub 2015 May 1.

Using SRM mass spectrometry to quantify nuclear protein abundance differences between adipose tissue depot of insulin-resistant mice.
Ota A, Kovary KM, Wu OH, Ahrenda R, Shen W, Costa MJ, Feldman BJ, Kraemer FB, and Teruel MN. J. Lipid Res. jlr.D056317. First Published on April 3, 2015,doi:10.1194/jlr.D056317

BMPR2 Promotes Mitochondrial Function and DNA Integrity Related to Endothelial Survival During Reoxygenation and Reversibility of Pulmonary Hypertension.
Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen P, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ and Rabinovitch M. Cell Metabolism, 2015 Apr 7; 21(4):596-608. doi:10.1016/j.cmet.2015.03.010.

The development of next-generation screening and diagnostic platforms will change diabetes care.
Kumar RB, Gupta M, Feldman BJ. Expert Rev Mol Diagn. 2015 Jan 13:1-4.

Characterization of Cre Recombinase Activity for In Vivo Targeting of Adipocyte Precursor Cells.
Krueger KC, Costa M, Du H, Feldman BJ. Stem Cell Reports. 2014 Dec 9; 3(6):1147-58.

Novel GATA6 Mutations in Patients with Pancreatic Agenesis and Congenital Heart Malformations.
Chao CS, McKnight KD, Cox KL, Chang AL, Kim SK, Feldman BJ. PLoS One, 10(2): e0118449, 2015.

The Role of Vitamin D In Reducing Cancer Risk and Progression.
Feldman D, Krishnan A, Swami S, Giovanucci E, Feldman B, Nature Reviews Cancer, (14)5:342-357, 2014.

A Plasmonic Chip for Biomarker Discovery and Diagnosis of Type-1 Diabetes.
Zhang, B, Kumar RB, Dai H, and Feldman BJ. Nature Medicine, 20(8): 948-953, 2014.

Cell Autonomous Regulation of Brown Fat Identity Gene UCP1 by Unliganded Vitamin D Receptor.
Malloy PJ, Feldman BJ. Mol Endocrinol. 2013 Aug 1. [Epub ahead of print] PMID: 23906633

Adipose circadian clocks: coordination of metabolic rhythms by clock genes, steroid hormones, and PPARs.
Krueger, KC, Feldman, BJ. Hormone Molecular Biology and Clinical Investigation. 2013 Aug;14(1):15. Review. Epub 2013 May 23.

Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V).
Armstrong SP, Seeber RM, Ayoub MA, Feldman BJ, Pfleger KD.
PLoS One. 2013 Jun 6;8(6):e65885. doi: 10.1371/journal.pone.0065885. Print 2013. PMID: 23762448

Circadian Rhythm Gene Per3 is an Inhibitor of the Adipocyte Fate.
Costa M, So AY, Kassik K, Krueger KC, Pillsbury ML, Fu Y, Ptacek LJ, Yamamoto KR, Feldman BJ. JBC. 2011 Mar 18;286(11):9063-70.Epub 2011 Jan 12. PMID: 21228270

Enhanced BRET technology for the monitoring of agonist-induced and agonist-independent interactions between GPCRs and β-arrestins.
Kocan M, Dalrymple M, Seeber R, Feldman B and Pfleger K. 2010 Front. Endocrin. doi: 10.3389/fendo.2010.00012

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis.
So AY, Bernal TU, Pillsbury ML, Yamamoto KR, Feldman BJ.
Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17582-7. Epub 2009 Oct 5. PMID: 19805059

Agonist-independent interactions between beta-arrestins and mutant vasopressin type II receptors associated with nephrogenic syndrome of inappropriate antidiuresis.
Kocan M, See HB, Sampaio NG, Eidne KA, Feldman BJ, Pfleger KD.
Mol Endocrinol. 2009 Apr;23(4):559-71. Epub 2009 Jan 29. PMID: 19179480

Glucocorticoids influence on mesenchymal stem cells and implications for metabolic disease.
Feldman BJ.
Pediatr Res. 2009 Feb;65(2):249-51. PMID: 19262295

Conservation analysis predicts in vivo occupancy of glucocorticoid receptor-binding sequences at glucocorticoid-induced genes.
So AY, Cooper SB, Feldman BJ, Manuchehri M, Yamamoto KR.
Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5745-9. Epub 2008 Apr 11. PMID: 18408151

Is your metabolism determined by (cell) fate?
Feldman BJ.
Pediatr Res. 2007 Jun;61(6):636-9. Review. PMID: 17426662

Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects.
Feldman BJ, Streeper RS, Farese RV Jr, Yamamoto KR.
Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15675-80. Epub 2006 Oct 9. PMID: 17030820

Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children.
Huang EA, Feldman BJ, Schwartz ID, Geller DH, Rosenthal SM, Gitelman SE.
J Pediatr. 2006 Jan;148(1):128-31. PMID: 16423613

Nephrogenic syndrome of inappropriate antidiuresis.
Feldman BJ, Rosenthal SM, Vargas GA, Fenwick RG, Huang EA, Matsuda-Abedini M, Lustig RH, Mathias RS, Portale AA, Miller WL, Gitelman SE.
N Engl J Med. 2005 May 5;352(18):1884-90. PMID: 15872203

Carbohydrate-deficient glycoprotein syndrome-associated pericardial effusion treated with corticosteroids and salicylic acid.
Feldman BJ, Rosenthal D.
Pediatr Cardiol. 2002 Jul-Aug;23(4):469-71. PMID: 12170369

The development of androgen-independent prostate cancer.
Feldman BJ, Feldman D.
Nat Rev Cancer. 2001 Oct;1(1):34-45. Review. PMID: 11900250

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